{"id":18019,"date":"2026-05-05T14:43:00","date_gmt":"2026-05-05T12:43:00","guid":{"rendered":"https:\/\/www.pharmanutra.it\/?p=18019"},"modified":"2026-10-22T14:43:18","modified_gmt":"2026-10-22T12:43:18","slug":"rickets-in-children","status":"publish","type":"post","link":"https:\/\/www.pharmanutra.it\/en\/rickets-in-children\/","title":{"rendered":"Rickets in children: causes, signs, and prevention in paediatric care"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">The role of vitamin D, calcium, and phosphorus in skeletal development<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Rickets is a <strong>disorder that affects skeletal development<\/strong> and occurs predominantly<strong> during the first years of life<\/strong>, a period characterised by <strong>rapid bone growth<\/strong>. Although it is now relatively rare in Western countries, owing to improved nutritional status and careful paediatric monitoring, it remains an important clinical and preventive health concern. <br>Understanding <strong>the mechanisms<\/strong> underlying rickets, its <strong>early signs<\/strong>, and <strong>preventive strategies<\/strong> enables timely intervention and helps protect children\u2019s bone health during a crucial stage of development.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What is rickets in children?<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Rickets is a condition characterised by <strong>impaired mineralisation of growing bones<\/strong>, mainly due to a <strong>deficiency of vitamin D<\/strong>, <strong>calcium<\/strong>, and\/or <strong>phosphorus<\/strong>. These nutrients play an essential role in skeletal formation and strengthening; inadequate levels may make bones more fragile and increase the risk of skeletal deformities.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The age group most commonly affected is generally <strong>between 6 and 24 months, when bone growth is particularly rapid<\/strong>. In some cases, <strong>vitamin D deficiency during pregnancy<\/strong> may lead to the appearance of early signs during the infant\u2019s first months of life. <strong>Limited exposure to sunlight<\/strong>, which is essential for endogenous vitamin D synthesis, is another relevant factor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Hypophosphataemic rickets: a distinct form<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">In addition to nutritional forms, <strong>hypophosphataemic rickets<\/strong> <strong>is a rare genetic condition<\/strong> that is unrelated to dietary vitamin D intake. In this form, the primary abnormality <strong>affects phosphorus metabolism<\/strong>, resulting in reduced blood phosphate levels. <br>This condition may cause<strong> bone weakness and joint pain<\/strong> and is diagnosed through specific blood tests and radiological investigations. Its management requires specialist assessment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Signs and symptoms of rickets in children<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The<strong> symptoms of rickets<\/strong> may initially be subtle and non-specific. The most common signs include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>restlessness and irritability<\/li>\n\n\n\n<li>excessive sweating<\/li>\n\n\n\n<li>fatigue and muscle weakness<\/li>\n\n\n\n<li>bone or joint pain<\/li>\n\n\n\n<li>delayed growth and psychomotor development<\/li>\n\n\n\n<li>difficulties during teething<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">In more advanced cases, the following may occur:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>skeletal deformities affecting the skull, lower limbs, or rib cage<\/li>\n\n\n\n<li>increased susceptibility to infections<\/li>\n\n\n\n<li>muscle cramps or, rarely, seizures<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Because bone deformities are a late sign, <strong>early diagnosis is essential<\/strong>. If suspicious symptoms occur, a paediatrician should always be consulted so that the necessary investigations can be initiated.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Preventing rickets: nutrition and sunlight exposure<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The prevention of rickets in children is based on two main pillars:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong><strong>Adequate nutrition<\/strong><\/strong><br>During pregnancy and throughout the child\u2019s first years of life, it is essential to ensure a balanced intake of nutrients involved in bone metabolism, particularly <strong>vitamin D, calcium, and phosphorus<\/strong>.<br><\/li>\n\n\n\n<li><strong><strong>Adequate exposure to sunlight<\/strong><\/strong><br>Cutaneous vitamin D synthesis occurs through exposure to sunlight. During the winter months, or under environmental conditions that limit time spent outdoors, this production may be insufficient.<\/li>\n<\/ol>\n\n\n\n<h2 class=\"wp-block-heading\">Vitamin D: differences between D2 and D3<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The term vitamin D encompasses two main forms:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>vitamin D2 (ergocalciferol)<\/strong>, which is derived from plant sources<\/li>\n\n\n\n<li><strong>vitamin D3 (cholecalciferol)<\/strong>, which is derived from animal sources or synthesised in the skin following exposure to sunlight<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Scientific evidence indicates that <strong>vitamin D3 is more effective than D2 at maintaining adequate serum vitamin D levels<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Dietary sources of Vitamin D<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Some foods can contribute to dietary vitamin D intake when introduced gradually and in amounts appropriate for the child\u2019s age:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>oily fish (salmon, mackerel, tuna)<\/li>\n\n\n\n<li>eggs (yolk)<\/li>\n\n\n\n<li>butter<\/li>\n\n\n\n<li>full-fat cheeses<\/li>\n\n\n\n<li>mushrooms<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">When diet and sunlight exposure are insufficient, the paediatrician may consider <strong>vitamin D supplementation<\/strong>, generally in oral formulations.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">When to consult a paediatrician<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Monitoring growth and skeletal development is part of routine paediatric care. When risk factors, suspicious symptoms, or conditions that may predispose a child to nutritional deficiencies are present, assessment by a healthcare professional is essential.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">________________________________________<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><em>This content is provided for informational purposes only and is not a substitute for advice from a doctor or paediatrician. For personalised guidance concerning a child\u2019s health, consultation with a healthcare professional is always recommended<\/em>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The role of vitamin D, calcium, and phosphorus in skeletal development Rickets is a disorder that affects skeletal development and occurs predominantly during the first years of life, a period characterised by rapid bone growth. Although it is now relatively rare in Western countries, owing to improved nutritional status and careful paediatric monitoring, it remains [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":18017,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[100,102],"tags":[134],"anno_documento":[180],"class_list":["post-18019","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-minerals-and-vitamins","category-muscles-and-joints","tag-pediatrics","anno_documento-180"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Rickets in children: symptoms, causes, and prevention<\/title>\n<meta name=\"description\" content=\"Rickets in children: discover the causes, symptoms and prevention strategies, including vitamin D, nutrition and safe sunlight exposure.\" \/>\n<meta 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