Iron and Maternal Health: A Clinical Priority from Preconception to Postpartum

Dr. Giuseppe Gullo, gynaecologist and Head of the Assisted Reproduction and Fertility Preservation Unit at AOOR Villa Sofia Cervello in Palermo, emphasizes the importance of iron supplementation in reproductive and perinatal health during his contribution at IMCID 2025.

The 9th edition of the International Multidisciplinary Course on Iron Deficiency (IMCID), held in Palermo last April, brought together experts from around the world to discuss the latest evidence on iron deficiency in clinical practice. During Session VI, dedicated to Gynaecology, Obstetrics, and Reproductive Medicine, Dr. Giuseppe Gullo shared his clinical perspective, stressing the value of iron supplementation for both maternal and foetal health.

Dr. Gullo, IMCID has become a leading platform for the discussion of iron deficiency. From a clinical perspective, what made this edition particularly relevant?

From my perspective, this event is a valuable opportunity to promote the exchange of knowledge among clinicians worldwide. In the field of obstetrics and gynaecology, it is crucial to improve iron supplementation throughout all phases—from the preconception period, to pregnancy, and during breastfeeding.

Iron deficiency is particularly relevant for women, especially during conception. What screening and treatment strategies do you consider most effective?

Proper supplementation during the preconception phase helps increase pregnancy rates—an essential factor in a time of declining birth rates. It also contributes to maternal and foetal well-being. As discussed during the session, it is essential to begin iron supplementation at least three months before conception to restore adequate levels of folate and haemoglobin.

What are the effects of iron deficiency on maternal and foetal health beyond anaemia? And which therapies are most effective in the postpartum period?

Iron therapy and maintaining good iron stores support faster recovery in the case of bleeding or postpartum haemorrhage. A solid iron reserve improves maternal well-being and reduces complications, even in spontaneous vaginal deliveries.

Dr. Gullo’s contribution to IMCID 2025 highlighted the importance of a proactive approach to managing iron deficiency in obstetric and gynaecological care. Initiating iron supplementation already in the preconception phase represents an effective strategy to improve implantation and pregnancy rates, enhance maternal and foetal health, and reduce complications during and after pregnancy.

The Abstract Book of the 9^th IMCID – International Multidisciplinary Course on Iron Deficiency, held in Palermo (Sicily, Italy) from 3 to 4 April 2025, has been published as Supplement n°3 of the last issue of May 2025 of the international journal Blood Transfusion (IF=2.4).
Download the abstract book here!