ApportAL® Vital and immune system
It is known that an optimal nutritional state can reduce the risk of viral infections and their consequences; in fact, nutrients have an impact on the development of the immune system.
The immune system is an interactive network of organs and cells, whose main function is to protect our organism from the attack of foreign microorganisms and pathogens, called antigens.
The immune system is divided into 2 different parts, characterized by the speed and specificity of reaction to the response. These are called innate and adaptive immune response.
The innate response is not specific and involves some types of cells of the immune system (e.g. macrophages) that provide to defend our organism immediately, activating already after a few minutes from the entry of the microorganism.
The adaptive immune response, instead, consists of highly specific reactions through the activity of immune cells called T lymphocytes and B lymphocytes, which possess the memory capacity for a specific antigen, so that it activates faster if the body comes into contact again.
Although the innate response is immediate, it often damages healthy tissues due to its lack of specificity; on the contrary, the adaptive response is precise, but it takes days or weeks before developing.
These two defense mechanisms work together efficiently to ensure a high protection of our body.
Unfortunately, however, these defense mechanisms are not always reactive, since there are several factors that can cause a decrease in the response, such as stress and inadequate nutrition, leading to a higher probability of being infected by pathogenic microorganisms that are not destroyed by our immune system.
The rigid environmental temperatures and adverse climatic conditions, even if they are not a direct cause of the onset of seasonal illnesses, can lead our body to be more susceptible to them. A good strategy, therefore, to defend against the symptoms and the incidence of infections is to strengthen the immune system in order to fight pathogens more effectively.
The role of vitamin D
Vitamin D is known as the vitamin of the sun, and represents a hormone fundamental for health promotion. It is normally produced on the skin following exposure to ultraviolet rays in sunlight.
Vitamin D is essential for the deposit of calcium in the bones and to give them solidity and resistance, as well as promoting the absorption of phosphorus.
In recent years, vitamin D has been the subject of numerous scientific studies that, in addition to its classic effects on the homeostasis of calcium and bones, highlight the importance of this vitamin in the prevention of health, strengthening the immune system.
Vitamin D, in fact, can positively modulate innate and adaptive immune responses. Vitamin D deficiency is associated with increased autoimmunity and increased susceptibility to infections.
In recent years, epidemiological data have shown that vitamin D deficiency is associated with a high frequency of the population to get sick. It has been reported that a low serum level of vitamin D in patients is positively correlated with morbidity in upper respiratory tract infections, including influenza. It is assumed that the increase in influenza cases in winter can be related to reduced exposure to sunlight.
From 5-6 years of age and, in particular, during adolescence, the recommended daily dose of vitamin D is 600-1,000 IU/day. In case of poor compliance, on the advice of the family doctor or pediatrician, it is possible to opt for intermittent administration, with weekly or even monthly doses, which vary in total between 18,000 IU and 30,000 IU.
However, the diet sometimes fails to guarantee an adequate nutritional status, so it is necessary to resort to the administration of multivitamin and multimineral products, especially in children and the elderly.
The ingredients contained in ApportAl® products may contribute to the normal function of the immune system, supporting the body with the right concentrations of these nutrients, such as vitamin D.
ApportAL® contains 19 nutrients that perform four main functions: immune, antioxidant, tonic-energizing and muscular. It is a suitable product for adults who need a quick recharge of energy to deal with all those situations related to the change of season or stressful periods that cause a sense of fatigue and physical and mental fatigue. It is particularly suitable for those who follow diets characterized by a reduced intake of one or more nutrients.
ApportAL® Vital contains 19 nutrients that perform three macroactivities: immune, tonic and energizing. It is a suitable product for all those who need a proper integration in the post-flu or post-surgery convalescence, for those who are more susceptible to seasonal infections and tend to get sick often, or for those who cannot follow varied and balanced diets, making them lacking in one or more nutrients.
The minerals contained in ApportAL® and ApportAL® Vital, such as iron, magnesium, zinc, iodine and selenium are formulated with the Sucrosomial® technology, a patent of Pharmanutra S.p.a, in which minerals are protected by a matrix of phospholipids and sucrose esters of fatty acids. This innovative technology allows a high absorption and excellent gastrointestinal tolerability of these nutrients.
Finally, the 5 Sucrosomial® minerals allow the ApportAL® products to have a stable formulation that makes them unique.
- Aranow C.; Vitamin D and the Immune System. J Investig Med. 2011 Aug; 59(6): 881–886.
- Charoenngam, et al.; Immunologic Effects of Vitamin D on Human Health and Disease. Nutrients. 2020 Jul; 12(7): 2097.
- Tomoka Ao, et al.; The Effects of Vitamin D on Immune System and Inflammatory Diseases. Biomolecules. 2021 Nov; 11(11): 1624.