Sucrosomial® Vitamin B12

ULTRAB12® is a formulation of vitamin B12 (cyanocobalamin) developed with Sucrosomial® Technology, designed to ensure optimised absorption and high tolerability, overcoming the absorption limitations of conventional forms of vitamin B12.

The ULTRAB12® formulation

ULTRAB12® is a formulation of Sucrosomial® Vitamin B12 that protects the nutrient from chemical degradation and reduces interactions within the gastric environment, overcoming all limitations associated with the absorption of conventional vitamin B12 thanks to a patented delivery system.

Sucrosomial® Technology enhances the intestinal transport of the vitamin and promotes its absorption, contributing to a greater availability of vitamin B12 compared to conventional formulations.

Scientific Research

A recent study* evaluated the efficacy and tolerability of Sucrosomial® vitamin B12 (ULTRAB12®) compared to conventional oral vitamin B12 formulations. The results showed a significantly higher intestinal absorption and improved tolerability, with no relevant adverse effects, thus confirming the safety and efficacy profile of the Sucrosomial® formulation.

*Memon N.M., et. al., Comparative bioavailability study of supplemental oral Sucrosomial® vs. oral conventional vitamin B12 in enhancing circulatory B12 levels in healthy deficient adults: a multicentre, double-blind randomized clinical trial. Front Nutri. 2024 Nov 8;11:1493593

Data sheet, safety data sheet (SDS) and technical documentation available upon request

Discover more about Sucrosomial® Technology®.

The physiological role of vitamin B12

Vitamin B12, or cobalamin, is an essential water-soluble vitamin involved in numerous physiological processes.
It contributes to the formation of red blood cells, the synthesis of nucleic acids and the maintenance of normal nervous system function.

Vitamin B12 is synthesised exclusively by bacteria and is mainly found in foods of animal origin.
Deficiency can occur in conditions of insufficient dietary intake (e.g. in vegetarians or vegans), in older adults, in pregnancy or in the presence of absorption disorders, such as digestive conditions or following bariatric surgery.

EFSA health claims

According to the European Food Safety Authority (EFSA), vitamin B12:

  • contributes to normal energy-yielding metabolism
  • contributes to normal functioning of the nervous system
  • contributes to normal homocysteine metabolism
  • contributes to normal psychological function
  • contributes to normal red blood cell formation
  • contributes to the normal function of the immune system
  • contributes to the reduction of tiredness and fatigue
  • has a role in the process of cell division

  • Optimised absorption – 2.5 times higher
  • High concentration of bioavailable vitamin
  • Patented delivery system
  • High tolerability
  • Suitable for vegan formulations
  • Non-GMO
  • Gluten- and lactose-free
  • Allergen-free
  • High stability

  • Solid supplements
  • Orodispersible supplements
  • Nutraceuticals
  • Gummies
  • Functional foods

Best for

Cells Cells
Energy Energy
Cognitive function Cognitive function
Muscle function Muscle function
Pregnancy and breastfeeding Pregnancy and breastfeeding
Memory Memory
Metabolism Metabolism
Blood Blood
Immune system Immune system
Nervous system Nervous system
Tiredness and fatigue Tiredness and fatigue